DNA damage response as a prognostic indicator in metastatic breast cancer via mutational analysis
نویسندگان
چکیده
منابع مشابه
Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer.
BACKGROUND Molecular screening programs use next-generation sequencing (NGS) of cancer gene panels to analyze metastatic biopsies. We interrogated whether plasma could be used as an alternative to metastatic biopsies. PATIENTS AND METHODS The Ion AmpliSeq™ Cancer Hotspot Panel v2 (Ion Torrent), covering 2800 COSMIC mutations from 50 cancer genes was used to analyze 69 tumor (primary/metastase...
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ژورنال
عنوان ژورنال: Annals of Translational Medicine
سال: 2021
ISSN: 2305-5839,2305-5847
DOI: 10.21037/atm-20-2137